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A second form of 2-γ PDT is so-called 2-photon2-color activation in which two independent short laser pulses are used sequentially in order i) to generate the S1 and hence the T1 state, and ii) to raise the T1 state to a higher Tn state, which then interacts with the biological substrate.

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5 68. Other orbitals are nonspherical, so, in addition to having shape, every orbital points in some direction. et al.

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